Introduction: Drug repurposing is fast growing and becoming an attractive approach for identifying novel targets, such as exosomes for cancer and antiviral therapy.Exosomes are a specialized class of extracellular vesicles that serve as functional mediators in intercellular communication and signaling that are important in normal physiological func
ABSTRACT Sumatran tigers (Panthera tigris sumatrae) are currently listed as critically endangered on the IUCN Red List.In modern zoos, the need to balance the welfare of tigers while maintaining visitor interest presents a significant challenge.The aim of this study was to assess the behaviour of five Sumatran tigers housed in two separate groups a
Summary: Background: Oligogenic inheritance has been suggested as a possible mechanism to explain the broad phenotype observed in individuals with differences Shoe Care Kits of sex development (DSD) harbouring NR5A1/SF-1 variants.Methods: We investigated genetic patterns of possible oligogenicity in a cohort of 30 individuals with NR5A1/SF-1 varian
Prostate cancer is the most common non-cutaneous neoplasm in the male population worldwide.It is typically diagnosed Hub Bearing in its early stages, and the disease exhibits a relatively indolent course in most patients.Despite the curability of localized disease with prostatectomy and radiation therapy, some patients develop metastatic disease an
In 2008, Ecuador reformed its Constitution after a prolonged period of economic, social and political crises.The momentary Sound Machine rupturing of power structures, that had limited political participation to small clusters of elites, opened participatory spaces for historically marginalised social groups to engage in the process of constitution